5 EASY FACTS ABOUT TRAMADOL (RETARD) DESCRIBED

Opioid activity is because of the two small affinity binding from the father or mother compound and better affinity binding in the O-demethylated metabolite M1 to μ-opioid receptors. In animal types, M1 is around 6 instances much more powerful than tramadol in developing analgesia and 200 occasions additional strong in μ-opioid binding.